239000002246 antineoplastic agent Substances 0.000 claims description 39.230000008313 sensitization Effects 0.000 claims description 40.206010070834 Sensitisation Diseases 0.000 claims description 40.BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 48.ZROHGHOFXNOHSO-BNTLRKBRSA-L (1R,2R)-cyclohexane-1,2-diamine oxalate platinum(2+) Chemical group ZROHGHOFXNOHSO-BNTLRKBRSA-L 0.000 claims description 48.150000002632 lipids Chemical class 0.000 claims description 63.NPDSHTNEKLQQIJ-ZJHFMPGASA-N α-dimorphecolic acid Chemical compound CCCCC\C=C/C=C/C(O)CCCCCCCC(O)=O NPDSHTNEKLQQIJ-ZJHFMPGASA-N 0.000 claims description 66.239000008194 pharmaceutical composition Substances 0.000 claims abstract description 15.230000003405 preventing Effects 0.000 title claims abstract description 14.208000004296 Neuralgia Diseases 0.000 title claims abstract description 30.238000002512 chemotherapy Methods 0.000 title claims abstract description 36.239000003112 inhibitor Substances 0.000 title claims abstract description 114.230000002401 inhibitory effect Effects 0.000 title claims abstract description 152.filed Critical Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. ![]() Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) Filing date Publication date Priority claimed from EP16190362.0 external-priority Application filed by Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Priority date (The priority date is an assumption and is not a legal conclusion. Inventor Susanne SCHIFFMANN Klaus Scholich Gerd Geisslinger Stephan HOHMANN Marco Sisignano Original Assignee Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Google Patents WO2018055082A1 - Inhibitors of gpr132 for use in preventing and/or treating chemotherapy-induced neuropathic pain WO2018055082A1 - Inhibitors of gpr132 for use in preventing and/or treating chemotherapy-induced neuropathic pain
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